Upset winners from Round 1 meet at Etihad Stadium on Saturday to fight over an unlikely 2-0 start to the season. 

St Kilda, undermanned and in the early stages of a long-term rebuild, beat Melbourne by 17 points with a depleted midfield, other experienced players out and three debutants. 

They look to have found a player in Luke Dunstan, who is this week's NAB AFL Rising Star nominee, while Tom Curren looks set to play an important role this year. 

Greater Western Sydney's round one triumph was more dramatic and caused bigger shockwaves, upsetting big brother the Sydney Swans with a 32-point win on March 15. 

Ex-Swan Shane Mumford showed why the GIANTS recruited him with a commanding performance in the ruck while Callan Ward, Stephen Coniglio and Adam Treloar were impressive and Jeremy Cameron kicked four goals - including the sealer - despite being well held by Ted Richards in the first half.  

WHERE AND WHEN: Etihad Stadium, Saturday March 29, 1.40pm

TV AND RADIO: Click here for the broadcast guide

LAST TWO TIMES

R3, 2013, St Kilda 21.14 (140) d GWS GIANTS 10.8 (68) at Manuka Oval

R22, 2012, St Kilda 25.13 (163) d GWS GIANTS 5.5 (35) at Etihad Stadium

THE SIX POINTS

1. David Armitage is under an injury cloud after pulling up with knee soreness. The Saints could use his midfield grunt given he managed four goals and 31 possessions last time the sides met, winning him three Brownlow medal votes.

2. It was a lopsided result when they faced off in round three last year at Manuka Oval. The Saints ran out 72-point winners on a disappointing day for the GIANTS, who also lost forward Jonathon Patton to a torn ACL.

3. The Saints' record at Etihad Stadium is tracking upwards thanks to three wins from their last three games. The Giants are searching for their first at the Docklands stadium after five tries.

4. The GIANTS shone in the midfield in round one. No team had more clearances than them with 55, while the Saints were ranked ninth with 40.

5. Neither side was impressive when it came to marks inside the forward 50. Both teams took eight marks for the game, which gave them an equal rating of 14th.

6. St Kilda midfielder and reigning best and fairest winner Jack Steven remains the highest-ranked player in the AFL Official Player Ratings from both teams despite being unavailable until at least round four because of a fractured foot. Ward showed some movement last week to rise to 28th after his impressive game.

Prediction: Greater Western Sydney by 10 points.